When the Message Goes Awry Disease-Producing Mutations that Influence mRNA Content and Performance
نویسندگان
چکیده
Mutations that cause disease commonly occur in the coding sequence and directly influence protein structure and function. However, many diseases result from mutations that influence various aspects of mRNA metabolism, including processing, export, stability, and translational control.
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عنوان ژورنال:
- Cell
دوره 107 شماره
صفحات -
تاریخ انتشار 2001